Comment by Independent-Rip-4373 on 19/01/2025 at 15:54 UTC

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There isn’t a lab created cleavage site. The wild progenitor readily attaches to human ACE2 receptors as is.

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Comment by Cautious-Progress876 at 19/01/2025 at 16:02 UTC

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The paper you cite specifically says these bat viruses lack the furin cleavage site found in SARS-CoV-2– a type of cleavage site that allows a virus to enter human cells more easily.