3 upvotes, 1 direct replies (showing 1)
There are a couple of studies that show similar improvements in long COVID patients following vaccination. https://www.bmj.com/content/bmj/377/bmj-2021-069676.full.pdf[1] https://www.mdpi.com/2076-393X/10/5/652[2] https://www.ijidonline.com/article/S1201-9712(23)00720-8/fulltext[3] Meta-analysis here. https://www.sciencedirect.com/science/article/pii/S0163445324002937[4]
1: https://www.bmj.com/content/bmj/377/bmj-2021-069676.full.pdf
2: https://www.mdpi.com/2076-393X/10/5/652
3: https://www.ijidonline.com/article/S1201-9712(23)00720-8/fulltext
4: https://www.sciencedirect.com/science/article/pii/S0163445324002937
Comment by AcornAl at 06/02/2025 at 05:11 UTC
1 upvotes, 1 direct replies
One-dose post-COVID vaccination was associated with a 15% reduced odds of long COVID (number of studies = 5, summary OR = 0.85, **95% CI = 0.73–0.98, p-value = 0.024**). The OR of two-dose post-COVID vaccination against long COVID was statistically insignificant but was far away from 1 (number of studies = 3, summary OR = 0.63, **95% CI = 0.38–1.03, p-value = 0.066**).
That's my interpretation of generally showing non-significant improvements when even the meta-review struggles to get a 95% CI that the results even show an improvement. :)
Anyways, these still reduce re-infections that carry the risk of relapses or making the symptoms worse. I'd haphazard this is behind most of the apparent benefits seen in many of these studies.