https://pubmed.ncbi.nlm.nih.gov/39901596/
created by RadioheadTrader on 04/02/2025 at 21:50 UTC
82 upvotes, 3 top-level comments (showing 3)
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1 upvotes, 0 direct replies
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Comment by RadioheadTrader at 04/02/2025 at 21:52 UTC
31 upvotes, 0 direct replies
Feb 4, 2025 - Abstract
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Abstract
Background: The positive effects of vaccination status on the course of Long COVID symptoms have not been fully elucidated. Our aim is to determine the most common Long COVID symptoms in patients monitored in the COVID-19 follow-up clinic and to examine whether there is a difference between the recovery rates of those who are vaccinated and those who are not vaccinated.
Method: Between December 1, 2020 and April 30, 2022, prospectively collected data of 916 patients who were admitted to the COVID-19 follow-up outpatient clinic of a tertiary hospital for the first time were evaluated as a retrospective cohort in this study. The frequencies of the ten most common symptoms in the first and last examinations of 478 patients with Long COVID symptoms were determined, and their recovery was compared. Patients were divided into two groups according to their vaccination status. The values showing the recovery rates obtained for these two groups were compared between themselves again.
Results: The average age of the patients in the study group was 54.43 ± 11.71 years, and 255 (53.3%) were male. The median follow-up period was 10 months. 84.7% of patients had received at least one dose of vaccine. Statistically significant results were found for improvement in all ten symptoms in vaccinated patients compared to the never-vaccinated group. There was no statistically significant difference between the CoronaVac, BNT162b2, and heterologous (CoronaVac+ BNT162b2) vaccine groups. Factors affecting recovery for the three most common symptoms (dyspnea, fatigue, forgetfulness) were examined with univariate logistic regression analysis, and only vaccination or non-vaccination was found to be a significant risk factor.
Conclusion: This study showed that receiving vaccination may be effective in improving Long COVID symptoms. Although there were no statistically significant differences between the inactive vaccine CoronaVac, the mRNA vaccine BNT162b2, and the heterologous (CoronaVac+ BNT162b2) vaccine in terms of reducing Long COVID symptoms, higher recovery rates were detected in those who received the mRNA vaccine BNT162b2
Comment by cos at 05/02/2025 at 04:33 UTC
3 upvotes, 1 direct replies
This is a retrospective of people who got covid mostly in 2021, separating those who got no vaccine at all from those who got a vaccine (but in most cases no booster).
We've had a number of other papers already over the past couple of years comparing long covid between totally unvaccinated vs. once-vaccinated people, from the first year or two after vaccines became available. Does this paper show anything particularly noteworthy that wasn't found by past papers? (I'm in favor of establishing reproducibility of results by publishing independently arrived at papers looking at the same thing, just curious if this one found anything particularly different)