Quote from BMJ OpenHeart Study on Omega-6 vegetable oils source:
The low-density lipoprotein (LDL) oxidation hypothesis gained traction during the 1980s because it was noted that in general, native unoxidised LDL does not cause foam cell formation. In other words, LDL had to become oxidised first in order for atherosclerosis to develop. Indeed, it was later discovered that oxidised LDL (oxLDL) caused direct toxic effects to the cell, recruitment and entry of monocytes into the subendothelial layer and increased foam cell formation leading to increased atherosclerosis and inflammation.
Oxidized LDL is toxic and enables hardening of the arteries and inflammation.
But it doesn’t say what else causes, just this one particular cause.
BMJ: OpenHeart Study on Omega-6 vegetable oils
Carved from raw notes on the study.
updated: 2024-01-13 11:26:20
generated: 2024-07-08