Following the passing of John Horton Conway, I made an NES implementation of Conway's Game of Life. This implementation has a 40x40 grid (non-wrapping) and runs pretty slowly, but does work.
Conway's Game of Life title screenshot
Conway's Game of Life game screenshot
I wrote a blog post titled "Implementing Conway's Game of Life on the NES" that goes into more details about this project.
Implementing Conway's Game of Life on the NES