This document contains more info about QC step 11.
https://docs.scipy.org/doc/scipy/reference/generated/scipy.stats.shapiro.html
https://vedexcel.com/how-to-perform-a-shapiro-wilk-test-in-python/
Here is a simple QC procedure we may want to consider that was used by Megan and Camron in a recent paper that I have attached. Phenotypes were assessed for normality using the Shapiro–Wilk Test. Because some of the data residuals devi- ated significantly from normality, we used the orderNorm function to perform Ordered Quantile normalization43 on all phenotypes. -- Rob
QTL analysis was performed in F2 mice using the R package R/qtl (RRID:SCR_009085) as previously described.11,29,42 Quality checking of genotypes and QTL analysis were performed in R (https://www.r- project.org/) using R/bestNormalize (https://github.com/petersonR/ bestNormalize) and R/qtl.42 Phenotypes were assessed for normality using the Shapiro–Wilk Test. Because some of the data residuals devi- ated significantly from normality, we used the orderNorm function to perform Ordered Quantile normalization43 on all phenotypes. QTL -- A quantitative trait variant in Gabra2 underlies increased methamphetamine stimulant sensitivity