Rapid Vitamin D Supplementation May Present Better Outcomes in Covid-19

Author: curmudgeon22

Score: 45

Comments: 12

Date: 2021-11-29 18:50:09

Web Link

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nradov wrote at 2021-11-29 19:25:01:

Here's the original full text study link.

https://www.mdpi.com/2072-6643/13/11/4047/htm

It looks interesting but I'm concerned that they describe hydroxychloroquine and azithromycin as "anti-virals". While some doctors attempted to use those medications to treat COVID-19, they were never confirmed to have any significant anti-viral effect. So that leads me to question the quality of the peer review process.

This other site has a fairly complete index of other studies on vitamin D and COVID-19. Taken as a whole there's pretty strong evidence that vitamin D deficiency is a serious risk factor. There's a real causative relationship; it's more than just a correlation with other risk factors like advanced age and obesity.

https://vitamin-d-covid.shotwell.ca/

bananabiscuit wrote at 2021-11-29 20:30:50:

Hydroxychloroquine was only conclusively proven to have no effect on already hospitalized patients with severe covid. It is now known that this is the point in the disease where the significant portion of viral activity has already taken place, so it would make sense that an anti-viral would no longer do anything at this point.

Last I checked there were no large trials for its use as early treatment, but some small trials do show that it can be effective if used early.

Here’s a summary:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7534595/

rsfern wrote at 2021-11-30 01:23:51:

I don’t know, there are only two randomized controlled trials for early treatment discussed in this paper. Neither had statistically significant results, but the review authors speculate that better statistical power would confirm the trend anyway…

I tried looking for something more recent, but I only found this actual meta analysis that I don’t think covers early treatment, but is not favorable for hydroxychloroquine as a treatment for Covid.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449662

treeman79 wrote at 2021-11-30 00:01:27:

Need good data on autoimmune patients who take it. A high risk group in general. How did they fair in aggregate?

I started Hydroxychloroquine about six months before covid for Sjogrens. Stopped after getting and recovering from Covid. Was out of commission for a month. Had a couple of rough nights and about six months of intense clotting. I had to double my blood thinners.

Of course no idea if it would have

been worse off or not.

On autoimmune forums it ranges from very effective with or without side effects to useless.

It was a huge help for my condition, but side effects were to much.

tamaharbor wrote at 2021-11-30 02:07:27:

Sorry Dude, this was a Trump thing, and you are probably getting a lot of down votes for it. But I agree we do need to treat early, acquire natural immunity, and not worry so much about continual vaccines and boosters.

jjeaff wrote at 2021-11-30 05:52:29:

I don't think there is any immunologist, virologist, or infectious disease doctor out there that agrees with your idea that you are better off getting infected with a disease than getting immunized for that disease.

nradov wrote at 2021-11-30 16:43:46:

I encourage everyone eligible to get vaccinated, however vaccination doesn't reliably prevent infection. Eventually most vaccinated people will be infected. Fortunately the vaccines are pretty good at preventing deaths.

https://www.cnbc.com/2021/08/12/herd-immunity-is-mythical-wi...

wsc981 wrote at 2021-11-30 06:56:59:

_> with your idea that you are better off getting infected with a disease than getting immunized for that disease._

With regards to COVID, no one is getting immunised through the vaccines right now as I understand?

kadoban wrote at 2021-11-30 12:06:30:

Immunization: A process by which a person becomes protected against a disease through vaccination. This term is often used interchangeably with vaccination or inoculation.

https://www.cdc.gov/vaccines/vac-gen/imz-basics.htm

tinus_hn wrote at 2021-11-30 00:30:37:

So has this been peer reviewed and has the data been verified?

This seems like such a simple idea I really don’t understand why this hasn’t been properly tested before.

nradov wrote at 2021-11-30 04:16:02:

Yes it has been peer reviewed. I can't vouch for the quality of that review, however other studies have reached similar results.

https://vitamin-d-covid.shotwell.ca/

justinsaccount wrote at 2021-11-30 01:51:38:

Sleeping with potatoes in your socks is also a simple idea.