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Diet soda tied to stroke risk, but reasons unclear

2011-02-10 06:35:59

By MARILYNN MARCHIONE, AP Medical Writer Marilynn Marchione, Ap Medical Writer

Wed Feb 9, 5:02 pm ET

LOS ANGELES It's far from definitive proof, but new research raises concern

about diet soda, finding higher risks for stroke and heart attack among people

who drink it everyday versus those who drink no soda at all.

The beverage findings should be "a wakeup call to pay attention to diet sodas,"

said Dr. Steven Greenberg. He is a Harvard Medical School neurologist and vice

chairman of the International Stroke Conference in California, where the

research was presented on Wednesday.

A simple solution, health experts say, is to drink water instead.

Doctors have no chemical or biological explanation for why diet soda may be

risky. It could be that people who drink lots of it also fail to exercise,

weigh more, drink more alcohol or have other risk factors like high blood

pressure and smoking. However, the researchers took these and many other

factors into account and didn't see a change in the trend.

"It's reasonable to have doubts, because we don't have a clear mechanism. This

needs to be viewed as a preliminary study," said lead researcher Hannah

Gardener of the University of Miami.

But for those trying to cut calories, "diet soft drinks may not be an optimal

substitute for sugar-sweetened beverages," she said.

The numbers come from the Northern Manhattan study, which enrolled about 2,500

adults over 40 in the New York area from 1993 to 2001 through random phone

calls. Half are Hispanic and one-fourth are black, making it one of the few

studies to look at these risks in minorities, who have higher rates of stroke.

Participants filled out a standard survey about their diets at the start of the

study, and their health was tracked for nearly 10 years. In that time there

were 559 strokes or heart attacks, 338 of them fatal.

Daily diet soda drinkers (there were 116 in the study) had a 48 percent higher

risk of stroke or heart attack than people who drank no soda of any kind (901

people, or 35 percent of total participants). That's after taking into account

rates of smoking, diabetes, waistline size and other differences among the

groups.

No significant differences in risk were seen among people who drank a mix of

diet and regular soda.

Earlier studies have tied diet and regular soda consumption to greater risk of

diabetes and a group of weight-related problems called the metabolic syndrome.

Some diet soda critics have suggested it can promote a sweet tooth, affecting

behavior and how much of a person's diet comes from sugary sources rather than

healthier fruits, vegetables and grains.

These sorts of studies just observe groups of people and are not strong enough

evidence to prove risk.

"It's too preliminary to suggest any dietary advice," but other big studies

should look at this question, Gardener said.

Greenberg, of the stroke association, called it "a real-world" look at possible

risk.

Dr. Maureen Storey, senior vice president of science policy for the American

Beverage Association, said in a statement that there is no evidence "that diet

soda uniquely causes increased risk of vascular events or stroke."

"The body of scientific evidence does show that diet soft drinks can be a

useful weight management tool, a position supported by the American Dietetic

Association. Thus, to suggest that they are harmful with no credible evidence

does a disservice to those trying to lose weight or maintain a healthy weight."

The beverage group's statement also noted researchers didn't adjust their

results for family history of stroke. Gardener, the researcher, said that's not

"a substantial weakness."

The same federally funded study also looked at a more conventional health risk

salt. It found higher risks for people eating more than 1,500 milligrams a

day. That's the limit the American Heart Association recommends, but last

week's new dietary guidelines from the government say it's OK to have a little

more.

Researchers found that stroke risk rose 16 percent for every 500 milligrams of

salt consumed each day. Those who took in 4,000 or more milligrams of salt had

more than 2.5 times greater risk of stroke compared to those who limited

themselves to 1,500 milligrams.

A teaspoon of salt contains about 2,300 milligrams of sodium. About

three-fourths of the salt we eat, though, comes from processed foods,

especially tomato sauce, soups, condiments, and canned foods.

___

Online:

Stroke conference: http://www.strokeconference.org

Heart Association on salt: http://bit.ly/GHA0W