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2017-07-20 10:26:00
By Fergus Walsh Medical correspondent
One in three cases of dementia could be prevented if more people looked after
their brain health throughout life, according to an international study in the
Lancet.
It lists nine key risk factors including lack of education, hearing loss,
smoking and physical inactivity.
The study is being presented at the Alzheimer's Association International
Conference in London.
By 2050, 131 million people could be living with dementia globally.
There are estimated to be 47 million people with the condition at the moment.
Nine factors that contribute to the risk of dementia
Mid-life hearing loss - responsible for 9% of the risk
Failing to complete secondary education - 8%
Smoking - 5%
Failing to seek early treatment for depression - 4%
Physical inactivity - 3%
Social isolation - 2%
High blood pressure - 2%
Obesity - 1%
Type 2 diabetes - 1%
These risk factors - which are described as potentially modifiable - add up to
35%. The other 65% of dementia risk is thought to be potentially
non-modifiable.
Source: Lancet Commission on dementia prevention, intervention and care
"Although dementia is diagnosed in later life, the brain changes usually begin
to develop years before," said lead author Prof Gill Livingston, from
University College London.
"Acting now will vastly improve life for people with dementia and their
families and, in doing so, will transform the future of society."
The report, which combines the work of 24 international experts, says lifestyle
factors can play a major role in increasing or reducing an individual's
dementia risk.
It examines the benefits of building a "cognitive reserve", which means
strengthening the brain's networks so it can continue to function in later life
despite damage.
Eve Laird, from Dumfries, is worried about dementia because her mum is living
with the condition.
She has decided to make some changes to her lifestyle.
"I'm terrible for eating processed foods and takeaways and I've really been
trying to cut back on that.
"I definitely drink a lot more water than I used to - and I don't drink as much
coffee now.
"I actually took part in the Edinburgh marathon. For that I joined the Dumfries
running club - I go there once a week."
She says she felt so much better for the exercise, and for improving her diet.
"I felt a lot healthier and mentally sharper as well. It's something I'd really
like to continue, but it is hard to stay on track."
"I just think the small changes can make such a big difference."
Failure to complete secondary education was a major risk factor, and the
authors suggest that individuals who continue to learn throughout life are
likely to build additional brain reserves.
Another major risk factor is hearing loss in middle age - the researchers say
this can deny people a cognitively rich environment and lead to social
isolation and depression, which are among other potentially modifiable risk
factors for dementia.
Another key message from the report is that what is good for the heart is good
for the brain.
'Positive changes'
Not smoking, doing exercise, keeping a healthy weight, treating high blood
pressure and diabetes can all reduce the risk of dementia, as well as
cardiovascular disease, and cancer.
The researchers say they did not have enough data to include dietary factors or
alcohol in their calculations but believe both could be important.
Dr Doug Brown, director of research at Alzheimer's Society, said: "Though it's
not inevitable, dementia is currently set to be the 21st Century's biggest
killer. We all need to be aware of the risks and start making positive
lifestyle changes."
Dr David Reynolds, chief scientific officer at Alzheimer's Research UK, said:
"Alongside prevention research, we must continue to invest in research to find
a life-changing treatment for people with this devastating condition."