💾 Archived View for gmi.noulin.net › mobileNews › 3061.gmi captured on 2023-06-14 at 16:40:36. Gemini links have been rewritten to link to archived content
⬅️ Previous capture (2023-01-29)
-=-=-=-=-=-=-
2011-04-19 05:02:28
Low levels of sunlight coupled with glandular fever could increase the risk of
developing multiple sclerosis (MS), say researchers.
There are many suspected risk factors for MS and the disease is known to be
more common away from the equator.
The study, in Neurology, suggested that low levels of sunlight could affect how
the body responds to infection.
The MS Society said the study, based on hospital admissions data in England,
added weight to existing evidence.
MS affects about 100,000 people in the UK and is more common in the north of
England than in the south.
There are also high levels of both vitamin D deficiency and MS in Scotland,
where the MS Society is considering carrying out separate research on a
possible link between the two. Around 10,500 people have MS in the country, the
highest prevalence of the condition in the world.
With MS the protective layer around nerves, known as the myelin sheath, becomes
damaged. Messages from the brain to the rest of the body are disrupted,
resulting in difficulty moving, muscle weakness and blurred vision.
Light plus virus
The researchers at the University of Oxford looked at all hospital admissions
in England between 1998 and 2005.
Continue reading the main story
Start Quote
Vitamin D is thought to be a key factor in the development of MS
End Quote Dr Doug Brown MS Society
They found 56,681 MS cases and 14,621 cases of glandular fever, which is caused
by the Epstein-Barr virus.
The study also used data from Nasa on sunlight intensity.
The researchers found that by just analysing sunlight, they could explain 61%
of the variation in the number of MS cases across England.
However when they combined the effect of sunlight and glandular fever, 72% of
the variation in MS cases could be explained.
Professor George Ebers, from the University of Oxford, said: "It's possible
that vitamin D[which is made when the skin is exposed to sunlight] deficiency
may lead to an abnormal response to the Epstein-Barr virus.
"More research should be done on whether increasing UVB exposure or using
vitamin D supplements and possible treatments or vaccines for the Epstein-Barr
virus could lead to fewer cases of MS."
Dr Doug Brown, head of biomedical research at the MS Society, said: "This work
adds weight to existing evidence that MS is caused by a number of factors
working in combination.
"Vitamin D has been closely studied in recent years and is thought to be a key
factor in the development of MS, we look forward to seeing more research
dedicated to this important area."
Pam Macfarlane, chief executive of the Multiple Sclerosis Trust, said: "Further
research is needed, but being able to accurately predict the risk of getting MS
and identifying preventative measures would be another step forward."
Studies in the UK have suggested that the MS prevalence rate in England and
Wales is between 100 and 140 per 100,000, about 170 in Northern Ireland and as
high as 190 in Scotland. Individual studies in Orkney have recorded rates of
over 200.
It has also been noted that areas of high MS prevalence around the world have
been settled by Scottish immigrants, according to the MS Trust.