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2010-06-06 04:18:56
Key scientists behind World Health Organization advice on stockpiling of
pandemic flu drugs had financial ties with companies which stood to profit, an
investigation has found.
The British Medical Journal says the scientists had openly declared these
interests in other publications yet WHO made no mention of the links.
It comes as a report from the Council of Europe criticised the lack of
transparency around the handling of the swine flu pandemic.
A spokesman for WHO said the drug industry did not influence its decisions on
swine flu.
Guidelines recommending governments stockpile antiviral drugs were issued by
WHO in 2004.
The advice prompted many countries around the world into buying up large stocks
of Tamiflu, made by Roche, and Relenza manufactured by GlaxoSmithKline.
A year after the swine flu pandemic was declared, stocks are left unused in
warehouses and governments are attempting to unpick contracts.
Conflict of interest
The BMJ, in a joint investigation with The Bureau of Investigative Journalism,
found that three scientists involved in putting together the 2004 guidance had
previously been paid by Roche or GSK for lecturing and consultancy work as well
as being involved in research for the companies.
Analysis
Continue reading the main story
Fergus Walsh
Medical correspondent, BBC News
Be open. Be transparent. That seems to be the key learning point for the WHO
from this joint investigation.
It is common practice for academic experts to work closely with the
pharmaceutical industry, such as getting funding for drug trials, or to be paid
for attending meetings.
On all clinical papers authors must publicly declare any competing interests.
So it is surely advisable that the WHO follows the same policy with its
advisors.
And there is surely no logic in refusing to name the members of the emergency
committee which advised the WHO about the pandemic.
To fail to do so presents an own goal to critics and conspiracy theorists.
Although the scientists involved had freely declared the links in other places
and said WHO asked for conflicts of interest forms prior to expert meetings,
the ties were not publically declared by WHO.
It is not clear whether these conflicts were notified privately by WHO to
governments around the world, the BMJ said, and a request to see conflict of
interest declarations was turned down.
In addition, membership of the "emergency committee" which advised WHO's
director general Margaret Chan on declaring an influenza pandemic has been kept
secret.
It means the names of the 16 committee members are known only to people within
WHO, and as such their possible conflicts of interest with drug companies are
unknown.
On its website, WHO says: "Potential conflicts of interest are inherent in any
relationship between a normative and health development agency, like WHO, and a
profit-driven industry.
"Similar considerations apply when experts advising the Organization have
professional links with pharmaceutical companies.
"Numerous safeguards are in place to manage possible conflicts of interest or
their perception.