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Date: Fri, 17 Dec 1993 13:45:37 -0500
From: "Jonathan B. Kamien" <jkamien@MOOSE.UVM.EDU>
Subject: Re: Marijuana
Sender: Drug Abuse Education Information and Research <DRUGABUS@UMAB.BITNET>
Message-id: <01H6L0WB08RM934W66@YMIR.Claremont.Edu>

On Wed, 15 Dec 1993, Ruth Hudson wrote:

> I am writing a brochure about marijuana.  I am looking for the
> lastest research on marijuana.  Can anyone help me on references
> concerning side effects, long-term effects (especially reproduction),
> and current medical uses?  Most of the material available seems to be
> from 1986 and want something a little more current.  Thanks.
>
> Ruth A. Hudson                                  Ph (817) 273-2772
> Substance Abuse Prevention Coordinator          Fx (817) 273-2744
> The University of Texas at Arlington
> Student Health Services                  Email: Ruth@Health.UTA.EDU
> ----------------------------------------------------------------------

Ruth, you might try the following references:

Scallet, A.C. Neurotoxicology of cannabis and THC - a review of chronic
exposure studies in animals Pharmacol. Biochem. Behav. 1991 40 671 676

Schwartz, R.H.  Heavy marijuana use and recent memory impairment
Psychiatric Annals      1991            80      82

Iversen, L.L. Medical uses of marijuana Nature 1993 365 12 13

Thomas, H. Psychiatric symptoms in cannabis users Br. J. Psychiat. 1993
163 141 149

Kelly, P. and Jones, R.T. Metabolism of tetrahydrocannabinol in frequent
and infrequent marijuana users J. Anal. Toxicol. 1992 16 228 235

Block, R.I. and Ghoneim, M.M.   Effects of chronic marijuana use on human
cognition       Psychopharmacology      1993    110     219     228

Block, R.I., Farinpour, R. and Braverman, K.    Acute effects of marijuana
on cognition - relationships to chronic effects and smoking techniques
Pharmacol. Biochem. Behav.      1992    43      907     917

Block, R.I., Farnham, S., Braverman, K. Noyes, R. and Ghoneim, M.M.
Long-term marijuana use and subsequent effects on learning and cognitive
functions related to school achievement: preliminary study In: Residual
Effects of Drugs on Behavior, Spencer, J.W. and Boren, J.J., eds. NIDA
Research Monograph 101 1990 101 96 111

The last three by Block and colleagues may be the best *chronic* studies
available.

Also, given that you are neighbors, you might want to get in touch with
the folks at UNTHSC (used to be TCOM) Department of Pharmacology in Fort
Worth. They have a significant presence in Substance Abuse Research and
are heading up the Substance Abuse Insitute of North Texas (SAINT).

Hope this helps, Jonathan