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Can stress turn your hair grey overnight?

It s a common tale, even said to have happened to Marie Antoinette. But as

Claudia Hammond finds out, it is difficult to get to the root of the problem.

In 1982, a pilot called Captain Eric Moody was all ready for quiet overnight

flight from Kuala Lumpur to Perth. The sky was clear and the crew were happy

because they had some extra Malaysian satay that night. But as they flew over

Java, an engine failed. And then another and another. Minutes later there were

no working engines left. In his calmest pilot s voice Moody made an

announcement: Good evening ladies and gentlemen, This is your captain

speaking. We have a small problem. All four engines have stopped. We are doing

our damnedest to get them going again. I trust you are not in too much

distress.

Eric Moody also showed little sign of being terrified as he managed to make an

emergency landing at Jakarta airport later he discovered that a plume of ash

from a volcano had knocked out all four engines. But within six months of the

incident he noticed that the tip of his quiff had turned white. Within a year

the rest of his hair had done the same.

Captain Moody is not alone. The same thing is said to have happened to several

historical figures, but in a far shorter time frame. When the French queen,

Marie Antoinette was led to the guillotine at the age of 37, her hair is said

to have turned white the night before in anticipation of her execution. The

English lawyer Sir Thomas More, who was later canonised, was executed in the

Tower of London in 1535, and again his hair was reported to have turned white

before his death.

These are good stories, but are they scientifically possible? Can hair really

turn white overnight? Is there a physiological process through which extreme

stress can cause hair to change colour this fast?

Sudden loss

Hair gets its colour from two types of melanin pigment eumelanin which

dictates how dark the hair is, and pheomelanin which determines how red or

yellow it is. As we age, the cells in hair follicles stop producing these

pigments and the resulting hairs are colourless. Eventually, the overall effect

of a combination of coloured and colourless hair, especially in people with

dark hair, is grey.

The process behind this is not well understood. One study showed that hair

naturally greys through the same chemical used to bleach hair from bottles. The

idea proposed from studies in mice is that melanin-making cells produce

hydrogen peroxide, which is normally broken down by an enzyme called catalase.

However, production of the enzyme drops as we age, and the build-up of hydrogen

peroxide blocks melanin production.

The medical name for the sudden whitening of the hair is canities subita. The

best explanation for it is not that the hair changes colour, but that the

pigmented hairs fall out. A condition called alopecia ariata causes the hair

shed suddenly, resulting in bald patches. It is thought to be caused by an

auto-immune response, where the body s defence system turns on itself. It can

be exacerbated by stress, which could account for the association of white hair

with terrifying experiences. In some cases the white hairs are unaffected by

the condition.

So a severe shock could trigger hair loss, but with only the coloured hairs

falling out, leaving someone who already has some grey with a whole head of

white hair. Or perhaps the immune response might target the pigment-producing

system, which would explain why those no follicles no longer producing coloured

hair are unaffected.

Shock spot

This explanation might well account for cases like that of Captain Moody. His

hair took a year to turn completely white. The overnight cases like Marie

Antoinette s are harder to explain. She was imprisoned for a year, so perhaps

she was denied hair dye in captivity and by the time she appeared in public

again at her execution with her hair cut short her grey roots had grown out.

But this doesn t explain other anecdotal tales, for instance in young people

who would have so few white hairs that if all their darker hair fell any white

hairs remaining would be very sparse. Then there s a more recent case study of

a 54-year-old woman in Switzerland who had a small patch of hair loss. She was

given steroids, which treated the hair loss successfully, but within a few

weeks all her hair had turned white, even though she had not had a frightening

experience and had stopped losing her hair.

Last year, a study from a research group led by no less than one of this year s

recipients of the Nobel prize in Chemistry, Robert Lefkowitz, offered some

clues. They outlined a mechanism through which a hallmark of chronic stress

causes DNA damage in mice that could lead to conditions like greying hair.

The puzzle of whether your hair can turn grey sounds like a simple one for

medical science to solve, but it s not. Ultimately, to study exactly what

happens you would need to examine the hair before and after a shocking

incident, carefully assessing its colour and thickness. Life-threatening

situations are not only rare, but unpredictable and no ethics committee is

going to let you induce a sufficiently terrifying experience in a lab

volunteer.

Yet there is something about the idea of hair changing colour through shock

that is fascinating. Maybe it s the idea that the body reveals more than we

think, that underneath the impressive calmness which allowed Captain Moody to

save the lives of 247 passengers, his body was telling a different story.

If you would like to comment on this article or anything else you have seen on

Future, head over to our Facebook page or message us on Twitter.

You can hear more Medical Myths on Health Check on the BBC World Service.

Disclaimer

All content within this column is provided for general information only, and

should not be treated as a substitute for the medical advice of your own doctor

or any other health care professional. The BBC is not responsible or liable for

any diagnosis made by a user based on the content of this site. The BBC is not

liable for the contents of any external internet sites listed, nor does it

endorse any commercial product or service mentioned or advised on any of the

sites. Always consult your own GP if you're in any way concerned about your

health.

http://www.bbc.com/future/story/20121016-can-stress-turn-your-hair-grey