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Brains of Buddhist monks scanned in meditation study

By Matt Danzico BBC News, New York

The study peers into brains of monks

In a laboratory tucked away off a noisy New York City street, a soft-spoken

neuroscientist has been placing Tibetan Buddhist monks into a car-sized brain

scanner to better understand the ancient practice of meditation.

But could this unusual research not only unravel the secrets of leading a

harmonious life but also shed light on some of the world's more mysterious

diseases?

Zoran Josipovic, a research scientist and adjunct professor at New York

University, says he has been peering into the brains of monks while they

meditate in an attempt to understand how their brains reorganise themselves

during the exercise.

Since 2008, the researcher has been placing the minds and bodies of prominent

Buddhist figures into a five-tonne (5,000kg) functional magnetic resonance

imaging (fMRI) machine.

The scanner tracks blood flow within the monks' heads as they meditate inside

its clunky walls, which echoes a musical rhythm when the machine is operating.

Dr Josipovic, who also moonlights as a Buddhist monk, says he is hoping to find

how some meditators achieve a state of "nonduality" or "oneness" with the

world, a unifying consciousness between a person and their environment.

Zoran Josipovic looking at brain scans on a computer The study specifically

looks at the default network in the brain, which controls self-reflective

thoughts

"One thing that meditation does for those who practise it a lot is that it

cultivates attentional skills," Dr Josipovic says, adding that those harnessed

skills can help lead to a more tranquil and happier way of being.

"Meditation research, particularly in the last 10 years or so, has shown to be

very promising because it points to an ability of the brain to change and

optimise in a way we didn't know previously was possible."

When one relaxes into a state of oneness, the neural networks in experienced

practitioners change as they lower the psychological wall between themselves

and their environments, Dr Josipovic says.

And this reorganisation in the brain may lead to what some meditators claim to

be a deep harmony between themselves and their surroundings.

Shifting attention

Dr Josipovic's research is part of a larger effort better to understand what

scientists have dubbed the default network in the brain.

He says the brain appears to be organised into two networks: the extrinsic

network and the intrinsic, or default, network.

Zoran Josipovic prepares a Buddhist monk for a brain scan in an fMRI machine Dr

Josipovic has scanned the brains of more than 20 experienced meditators during

the study

The extrinsic portion of the brain becomes active when individuals are focused

on external tasks, like playing sports or pouring a cup of coffee.

The default network churns when people reflect on matters that involve

themselves and their emotions.

But the networks are rarely fully active at the same time. And like a seesaw,

when one rises, the other one dips down.

This neural set-up allows individuals to concentrate more easily on one task at

any given time, without being consumed by distractions like daydreaming.

"What we're trying to do is basically track the changes in the networks in the

brain as the person shifts between these modes of attention," Dr Josipovic

says.

Dr Josipovic has found that some Buddhist monks and other experienced

meditators have the ability to keep both neural networks active at the same

time during meditation - that is to say, they have found a way to lift both

sides of the seesaw simultaneously.

And Dr Josipovic believes this ability to churn both the internal and external

networks in the brain concurrently may lead the monks to experience a

harmonious feeling of oneness with their environment.

Self-reflection

Scientists previously believed the self-reflective, default network in the

brain was simply one that was active when a person had no task on which to

focus their attention.

But researchers have found in the past decade that this section of the brain

swells with activity when the subject thinks about the self.

The default network came to light in 2001 when Dr Marcus Raichle, a neurologist

at the Washington University School of Medicine in the US state of Missouri,

began scanning the brains of individuals who were not given tasks to perform.

The patients quickly became bored, and Dr Raichle noticed a second network,

that had previously gone unnoticed, danced with activity. But the researcher

was unclear why this activity was occurring.

Other scientists were quick to suggest that Dr Raichle's subjects could have

actually been thinking about themselves.

Start Quote

It's a major and understudied network in the brain that seems to be very

involved in a lot of neurological disorders, including autism and Alzheimer's

End Quote Cindy Lustig University of Michigan, associate professor of

neuroscience

Soon other neuroscientists, who conducted studies using movies to stimulate the

brain, found that when there was a lull of activity in a film, the default

network began to flash - signalling that research subjects may have begun to

think about themselves out of boredom.

But Dr Raichle says the default network is important for more than just

thinking about what one had for dinner last night.

"Researchers have wrestled with this idea of how we know we are who we are. The

default mode network says something about how that might have come to be," he

says.

And Dr Raichle adds that those studying the default network may also help in

uncovering the secrets surrounding some psychological disorders, like

depression, autism and even Alzheimer's disease.

"If you look at Alzheimer's Disease, and you look at whether it attacks a

particular part of the brain, what's amazing is that it actually attacks the

default mode network," says Dr Raichle, adding that intrinsic network research,

like Dr Josipovic's, could assist in explaining why that is.

Cindy Lustig, associate professor of psychology and neuroscience at the

University of Michigan, agrees.

"It's a major and understudied network in the brain that seems to be very

involved in a lot of neurological disorders, including autism and Alzheimer's,

and understanding how that network interacts with the task-oriented [extrinsic]

network is important," she says. "It is sort of the other piece of the puzzle

that's been ignored for too long."

Dr Josipovic has scanned the brains of more than 20 experienced meditators,

both monks and nuns who primarily study the Tibetan Buddhist style of

meditation, to better understand this mysterious network.

He says his research, which will soon be published, will for the moment

continue to concentrate on explaining the neurological implications of oneness

and tranquillity - though improving understanding of autism or Alzheimer's

along the way would certainly be quite a bonus.