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Study: Love music? Thank a substance in your brain

By MALCOLM RITTER, AP Science Writer Malcolm Ritter, Ap Science Writer Sun

Jan 9, 1:23 pm ET

NEW YORK Whether it's the Beatles or Beethoven, people like music for the

same reason they like eating or having sex: It makes the brain release a

chemical that gives pleasure, a new study says.

The brain substance is involved both in anticipating a particularly thrilling

musical moment and in feeling the rush from it, researchers found.

Previous work had already suggested a role for dopamine, a substance brain

cells release to communicate with each other. But the new work, which scanned

people's brains as they listened to music, shows it happening directly.

While dopamine normally helps us feel the pleasure of eating or having sex, it

also helps produce euphoria from illegal drugs. It's active in particular

circuits of the brain.

The tie to dopamine helps explain why music is so widely popular across

cultures, Robert Zatorre and Valorie Salimpoor of McGill University in Montreal

write in an article posted online Sunday by the journal Nature Neuroscience.

The study used only instrumental music, showing that voices aren't necessary to

produce the dopamine response, Salimpoor said. It will take further work to

study how voices might contribute to the pleasure effect, she said.

The researchers described brain-scanning experiments with eight volunteers who

were chosen because they reliably felt chills from particular moments in some

favorite pieces of music. That characteristic let the experimenters study how

the brain handles both anticipation and arrival of a musical rush.

Results suggested that people who enjoy music but don't feel chills are also

experiencing dopamine's effects, Zatorre said.

PET scans showed the participants' brains pumped out more dopamine in a region

called the striatum when listening to favorite pieces of music than when

hearing other pieces. Functional MRI scans showed where and when those releases

happened.

Dopamine surged in one part of the striatum during the 15 seconds leading up to

a thrilling moment, and a different part when that musical highlight finally

arrived.

Zatorre said that makes sense: The area linked to anticipation connects with

parts of the brain involved with making predictions and responding to the

environment, while the area reacting to the peak moment itself is linked to the

brain's limbic system, which is involved in emotion.

The study volunteers chose a wide range of music from classical and jazz to

punk, tango and even bagpipes. The most popular were Barber's Adagio for

Strings, the second movement of Beethoven's Ninth Symphony and Debussy's Claire

de Lune.

Since they already knew the musical pieces they listened to, it wasn't possible

to tell whether the anticipation reaction came from memory or the natural feel

people develop for how music unfolds, Zatorre said. That question is under

study, too.

Dr. Gottfried Schlaug, an expert on music and the brain at Harvard Medical

School, called the study "remarkable" for the combination of techniques it

used.

While experts had indirect indications that music taps into the dopamine

system, he said, the new work "really nails it."

Music isn't the only cultural experience that affects the brain's reward

circuitry. Other researchers recently showed a link when people studied

artwork.