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Will We Ever Get Rid of Covid-19?

Author: theafh

Score: 30

Comments: 31

Date: 2021-11-30 16:19:50

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Nevermark wrote at 2021-11-30 17:34:49:

Yes, because the longer Covid hangs around, the faster virus fighting tech is going to improve.

Even better.

The combination of today's fast advancing technical knowledge, paired with the deadliness and globalness of Covid, relationships to HIV in terms of amplified risk, and the common cold and flu, has triggered a highly funded and increasingly organized war, waged with new weapons increasingly generalizable across viruses.

This war started with an unusual bang of many "small" battles won surprisingly quickly, which will maintain commitment and momentum needed for the war. Which given the world's inequalities will not be short.

Like the world entering the Holocene, our immune systems are entering into the era of routinely engineered support. Watchful preparedness, with engineering and distribution systems for resistance, mitigation and cures.

Eventually we will get to routine rapid detection, isolation and extinction. Perhaps even going so far as to eliminate threatening viruses in wildlife. Although that is far off.

cashsterling wrote at 2021-11-30 18:13:26:

Will we completely eradicate SARS-CoV-2 and its various mutations... no.

Will we reach a point where SARS-CoV-2, and its various mutations, are no longer a significant public health concern and we can return to "life as usual"... yes.

lopis wrote at 2021-11-30 18:54:23:

What exactly makes you think that? If covid disease gets a refresh every couple years like the flu does, it's not impossible that we never, ever get rid of it. It could just become a disease you just expect to get once you're older, unless humans as a species grow immune to it (read that as: lots of us die and only people with resistance to the virus get to breed for a generation or two).

cashsterling wrote at 2021-11-30 19:58:50:

Yep... it will continue to mutate and we will always have some SARS-CoV-2, as is the case with the flu.

SARS-CoV-2 will probably mutate over time to become less virulent but more transmissible. Vaccines and immune system adaptation will allow most of us to not worry about COVID too much until our later years in life, much like the flu.

COVID will continue to cause some deaths, but at a much lower level which is generally acceptable, as is the case with the flu.

mckirk wrote at 2021-11-30 23:53:10:

The flu mutates at a way faster rate, though. If the current pandemic was caused by an influenza virus, you'd have a whole lot more strains to worry about.

We're only seeing 'this many' Covid variants, because right now it has so many hosts to work with. Whether through vaccination or infection, that will change over time however.

TrevorJ wrote at 2021-11-30 19:09:58:

I'm not certain that what you describe is different than what the OP is saying.

sjg007 wrote at 2021-11-30 19:23:42:

Or it kills us all but not the bats or deer or dogs.

shoto_io wrote at 2021-11-30 17:23:49:

Yes.

We already have 4 other Corona Viril endemic in the human population. They probably all started out super deadly in a pandemic. This one will be endemic soon, too (1-2 years I assume).

somewhereoutth wrote at 2021-11-30 19:09:11:

We have zero evidence that the common cold coronas were previously any more deadly than they are now. Zero evidence.

Unfortunately the idea that Covid becomes just another common cold virus can be no more than wishful thinking at this point.

Without vaccines and public health interventions, likely SARS-COV-2 would continue washing through the population, with waning immunity and variants causing endless sickness and death, much as smallpox, polio, measles etc used to before we got a handle on them.

s1artibartfast wrote at 2021-11-30 19:47:46:

>Unfortunately the idea that Covid becomes just another common cold virus can be no more than wishful thinking at this point.

It is not wishful thinking that in the future, child exposure and adult immunity will be the norm.

Covid _is already_ just another common cold for the young.

Covid infection fatality rate for children is on the order of 1/100,000, similar to influenza or varicella (chicken pox), but much more dangerous for the elderly without immunity (like influenza or varicella).

This is drastically different than something like smallpox, which had a 30% fatality rate.

somewhereoutth wrote at 2021-11-30 20:15:13:

Just going by your IFR figures for Covid, without even considering hospitalisations and long term effects, it is certainly _not_ just another common cold for the young.

Furthermore, we don't know what if any protection childhood infection would give later in life - certainly reinfection in adults is common, with no guarantee that symptoms are less severe.

To take any approach that allows the widespread circulation of Covid is reckless at best at this moment, particularly when we _do_ have the tools available to us to control it (mandatory vaccination and targeted lockdowns).

s1artibartfast wrote at 2021-11-30 20:34:29:

>Just going by your IFR figures for Covid, without even considering hospitalizations and long term effects, it is certainly not just another common cold for the young.

This is exactly what the numbers support. both diseases have deaths on the order of 1/100,000 inflections for young children.

>Furthermore, we don't know what if any protection childhood infection would give later in life - certainly reinfection in adults is common, with no guarantee that symptoms are less severe.

All of the covid data we have suggests that infection symptoms are less severe if people have immunity from vaccine or prior illness.

>To take any approach that allows the widespread circulation of Covid is reckless at best at this moment, particularly when we do have the tools available to us to control it (mandatory vaccination and targeted lockdowns).

Vaccines and lockdowns can help control the spread, but will never be enough to prevent it from being endemic. Vaccinated individuals can spread the disease and it is in animal populations around the world.

somewhereoutth wrote at 2021-11-30 21:28:15:

Please can you provide some sources for the childhood IFR of the common cold? I can't find anything myself. I suspect your numbers are very wrong.

Please also provide sources for subsequent reinfection (as opposed to vaccination) being less severe.

Lockdowns have certainly worked in China (20% of the world's population), so it _is_ possible, if we choose it.

(to my knowledge, no significant outbreak has occurred from spillback)

shoto_io wrote at 2021-11-30 21:37:33:

"Lockdowns have worked".

Depends on how you define "have worked". If you optimize for just variable (COVID infections), then yes, they have worked. Until now.

If you look at the entire system, they have failed miserably.

robotresearcher wrote at 2021-11-30 20:11:04:

> Covid is already just another common cold for the young.

> Covid infection fatality rate for children is on the order of 1/100,000, similar to influenza or varicella (chicken pox)

Aren't flu and chicken pox an order of magnitude or two (or three?) more deadly than the common cold in children?

s1artibartfast wrote at 2021-11-30 20:48:33:

Chicken pox _case_ fatality was ~ 1/100,000 among children age 1 through 14 years before vaccines were introduced per the CDC.

https://www.cdc.gov/vaccines/pubs/pinkbook/varicella.html

robotresearcher wrote at 2021-11-30 21:35:13:

Glad to hear it. And deaths from the common cold?

mbg721 wrote at 2021-11-30 21:35:41:

Let's hope for none.

shoto_io wrote at 2021-11-30 21:34:54:

"Zero evidence", "Wishful thinking". No Sir. Just common sense.

They 4 other CoV have been studied extensively and there are also theories about their origins. You are taking very different types of virii and compare them with a Corona Virus, which makes no sense at all.

The question you need to answer: Why should this CoV be so different than the 4 others we know?

Btw: Common colds can be very deadly if your immune system is weak or not familiar with them. Just go and ask some native Americans back in the 1640s.

somewhereoutth wrote at 2021-11-30 23:00:35:

Why should it be the same? Why shouldn't it be like its nearest relatives, SARS-1 and MERS? (10% and 50% CFR).

As for the common cold and native Americans, you will need to ask them yourself - my understanding is that the common cold viruses have always been globally widespread. Please correct me if I'm wrong!

shoto_io wrote at 2021-11-30 23:04:31:

Because there is a reason they have been given the same name. They belong to the same family of virii. There are studies showing that exposure to one CoV induces immunity to the other.

Here is just one paper around that topic:

https://pubmed.ncbi.nlm.nih.gov/34273512/

lopis wrote at 2021-11-30 18:55:22:

So what you mean is actually "No", we won't get rid of it.

shoto_io wrote at 2021-11-30 21:45:44:

I think we will get rid of Covid-19, which is the disease. It will be just another common cold virus.

But, "no", we will never get rid of SARS-CoV-2 (the virus).

akagusu wrote at 2021-11-30 20:12:15:

Covid is the goose of the golden eggs. As long as the Big Pharma is making money, Covid is here to stay.

peakaboo wrote at 2021-11-30 20:19:32:

It's about much more than money. Society transformation with covid passes, which will become citizen passes.

Later the history books will mention covid as the catalyst for world transformation and it won't say a peep about the money that was made, because it doesn't matter.

MrMan wrote at 2021-11-30 19:09:14:

definitely not

Incerto wrote at 2021-11-30 17:17:28:

No.

verdverm wrote at 2021-11-30 17:21:35:

Well maybe, when we graduate to accepting the endemic nature, we'll stop appending the year to it

somewhereoutth wrote at 2021-11-30 19:15:41:

Maybe when we've suppressed it as we have with measles. Otherwise, as we have seen with Alpha, Beta, Delta and now Omicron, new variants will keep arising and keep making people very sick.

Smallpox used to be endemic, Polio used to be endemic, measles used to be endemic. That is not where we want to end up at.

How do we stop this? The same way we did with the others - comprehensive vaccination, mandated if necessary. Lockdowns on any outbreaks.

Ekaros wrote at 2021-11-30 21:39:21:

Vaccines make me doubtful as we don't yet have sterilising solution. And long term effectiveness is still questioned. What we now have with our inter-connected globalized world make it really hard to get rid off...

somewhereoutth wrote at 2021-11-30 23:07:21:

Indeed - they do seem to wane, for symptomatic infection anyway, and we see what happens regarding hospitalisations. Hopefully boosters will provide longer protection. Definitely a learning process.

anonnyj wrote at 2021-11-30 18:02:12:

Why kill the golden goose that provides lifetime vaccine subscription $$ for Pfizer, etc?

I'm wondering what we will call the variants after we run out of letters. Maybe they'll start to look like GPUs.

Latest Covid23000 GTX 600 series variant from Vietnam released, here's why doctors and investors are worried!

KiranRao0 wrote at 2021-11-30 19:47:40:

Betteridge's law of headlines: "Any headline that ends in a question mark can be answered by the word no."

https://en.wikipedia.org/wiki/Betteridge%27s_law_of_headline...