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From: andersom@spot.Colorado.EDU (Marc Anderson)
Newsgroups: alt.drugs,alt.psychoactives
Subject: Cannabis increases CBF!
Message-ID: <1993Apr22.203424.9887@ucsu.Colorado.EDU>
Date: 22 Apr 93 20:34:24 GMT
With all the talk about how bad cocaine is bad because it reduces cerebral
blood flow (CBF)/ glucose expenditure, I bumped into some research that found
cannabis increases CBF in the right and left frontal lobes and the left
temporal lobe.
This would be a good thing to throw at a drug warrior who claims cocaine is
bad because it decreases CBF. (ask him, "does this mean that cannabis is good
because it increases CBF?" -- of course it doesn't, but it's a good thing to
know anyway..)
[Mathew, R.J.; Wilson, W.H. (1993): Acute changes in cerebral blood flow
after smoking marijuana. _Life Sciences_. 52(8):757-767.]
Abstract:
In experienced marijuana smokers, marijuana smoking was accompanied
by a significant bilateral increase in cerebral blood flow (CBF)
especially in the frontal regions and cerebral blood velocity. The
post-marijuana CBF increase could not be explained on the basis on
changes in general circulation or respiration. Similarly, the CBF
increase was unrelated to plasma levels of tetrahydrocannabinol and
extracranial circulation. Behavioral changes showed significant
correlations with CBF. CBF and brain function are closely coupled and
therefore it seemed highly likely that CBF changes after marijuana were
closely related to its effect on mood and behavior.
-marc
andersom@spot.colorado.edu