Retinoic acid regulates both expression of the nerve growth factor receptor and sensitivity to nerve growth factor.

Created: 2021-08-07T00:30:12-05:00

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[retinoic acid]-treated cells are more sensitive to NGF, but not to either fibroblast growth factor or phorbol 12-myristate 13-acetate, showing that [retinoic acid] has a specific effect on the responsiveness of PC12 cells to NGF.