konspire [1] looks interesting—a P2P (Person to Person) filesharing system with a “channel” concept, which looks similar to NNTP (NetNews Transport Protocol) but without the administrative nightmare. Oliver Willis [2] (link via InstaPundit [3]) seems to be using it to “broadcast” his own show. I know my friend Kelly [4] had expressed interest in making a multimedia blog and was concerned about setting up streaming video; this might be something he might want to look into.
[1] http://konspire.sourceforge.net/howItWorks.shtml
[2] http://www.oliverwillis.com/entries/0603/be_the_broadcast.html