Comment by hatsune_aru on 22/09/2022 at 08:38 UTC

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View submission: Google's Alphafold breakthrough allows us to see what a protein looks like, but how does this help create new medicine?

the functionality of protein largely depends on the final folded shape, and the problem of predicting the folded shape based on the amino acid chain it was made from is a hard problem (which is what the field of protein folding is supposed to solve).

the folded protein has features that need to be in the right spot and in the right shape for it to work with the existing chemistry inside your body--that's why the folded shape is important.

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