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View submission: How significant is fever in suppressing virus outbreaks?
no evidence that taking ibuprofen to suppress a fever and body aches does anything harmful
Vaccines are a tangential subject to OP question, though echoing on the above with sources, prophylactic antipyretics do not affect efficacy of vaccines in children[1]. However, in adults, prophylactic antipyretic medications may reduce efficacy in some vaccines[2]. Therapeutic administration does not appear to markedly reduce antibody efficacy.
2: https://www.nature.com/articles/s41541-019-0132-6
As u/cl733 states, there are small reviews on “letting fever ride” vs standard of care showed reduced length of illness[3], though they are small studies, poorly performed, or contain complicated patient pictures.
3: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703655/
In all, the vast majority of non-critically ill patients will benefit from decreased fever, inflammation, and other subjective measures of illness. In a critical care setting, the picture becomes much more complicated and likely requires more nuance.
There's nothing here!