2 upvotes, 0 direct replies (showing 0)
View submission: How common is prion resistance/immunity in humans?
You could say that autophagy, especially macroautophagy, is an internal mechanism for prion resistance. Protein misfolding and aggregation, also called proteotoxicity, is something that all life forms have to deal with. So we have many mechanisms to deal with this. Many diseases that have been mentioned in this thread generally develop because these systems are overwhelmed or bypassed.... hope this helps you sleep.
Edit: I'll add that there are also prion-like proteins that are a part of your normal physiology. CPEB3 is one of them, and it's important for your memories!
There's nothing here!