Comment by GrumpyOldMillennialx on 13/03/2025 at 14:03 UTC

1 upvotes, 1 direct replies (showing 1)

View submission: Ask Anything Wednesday - Biology, Chemistry, Neuroscience, Medicine, Psychology

Does getting measles wipe your immunity even if you are vaccinated against it and still catch it?

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Comment by 095179005 at 13/03/2025 at 15:03 UTC*

1 upvotes, 0 direct replies

~~It depends.~~

I don't think so.

If you got infected just because you got a high viral dose, and still have a healthy amount of immunity/antibodies for measles, then the infection should be mild.

~~If you get infected because your body didn't gain immunity from the vaccine, then there is a risk of immune amnesia.~~

The fourth and most striking observation was the magni- tude (PRN titers >30,000) of the neutralizing antibody re- sponse in SVF(secondary vaccine failure) cases, which has not, as a rule, been observed following vaccination or primary acute measles. Although these individuals lacked sufficient protective neutralizing an- tibody to completely inhibit measles infection at the time of exposure, they rapidly mounted an impressive neutralizing response that likely mitigated extensive viral replication and resulted in mild measles with minimal symptoms and few complications.

Laboratory Characterization of Measles Virus Infection in Previously Vaccinated and Unvaccinated Individuals

https://www.jstor.org/stable/41230505

Measles vaccination also seems to cross protect you from other illnesses.

https://doi.org/10.1016/j.jinf.2023.07.010