Comment by Indemnity4 on 17/03/2023 at 03:29 UTC*

2 upvotes, 1 direct replies (showing 1)

View submission: Ask Anything Wednesday - Biology, Chemistry, Neuroscience, Medicine, Psychology

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are there studies being conducted on the effects of microplastics on a cellular level?

Yes! Science[1] and Nature[2] (both paywall) discuss this a lot.

1: https://www.science.org/doi/10.1126/science.abe5041#:~:text=Once%20in%20contact%20with%20epithelial,which%20could%20also%20act%20cumulatively.

2: https://www.nature.com/articles/d41586-021-01143-3

You ingest or inhale about 100,000 microplastic particles every day. One hundred thousand - that's a lot of particles!

However, that is under 4% of all the particles you consume every day. The whole world is made up of particles. Rocks, dirt, soil, bits of living tissue, lots of things.

However, at end-of-life autopopsies find only about 1000 microplastic particles in your entire body. Almost all of the microplastics don't interact with your body at all - they pass through your digestive track or out your lungs as easy as a ghost goes through a wall. So over 80 or so years, ingesting 100,000 a day, only a miniscule fraction carry across into your body.

That means we are looking for tiny effects. Maybe be signficiant later, but it's still very needle-in-a-haystack problem right now.

There are studies where animals are deliberately loaded up with microplastics[3] - and nothing happens.

3: https://www.nationalgeographic.com/environment/article/microplastics-are-in-our-bodies-how-much-do-they-harm-us

We know the particles are there, what we don't know about is potential sources of exposure, length of exposure, concentration effects, it hasn't even been linked with any follow-on effects different from conventional material particulates.

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Comment by mottavader at 17/03/2023 at 04:13 UTC

1 upvotes, 1 direct replies

Ah. Ok, interesting. I was just wondering about plastics on a molecular level and if they have adverse effects in general or only if they are coupled with a substance like bisphenol A for instance. I suppose we're going to find out sooner or later. Thanks so much for the links, hopefully I can find a way to circumvent the paywall to read up on this further. Much appreciated 😊