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No. That's a work of fiction. Nor, IMO, is it rational for people to feel like they have some kind of right to choose to put other people at risk deliberately, ignore science, and resist getting vaccinated or wearing masks.
But to get back on point - Rand actually wrote about when it would be time to shrug - and there was only one condition in her opinion that qualified. If we lose the 1st Amendment, specifically if Gov't suppresses the right to express our opinion, then it's over and time to walk away. Not before.
There's nothing here!